Lemtrada : Alemtuzumab 12 Mg Injection

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Brand Name : LEMTRADA
Composition : Alemtuzumab
Manufactured by : GENZYME Pharmaceuticals Ltd.
Strength : 12 mg 
Form : Injection
Packing : Pack of 1 Vial

SKU: LEMTRADA Category: Tag:


Buy Lemtrada : Alemtuzumab 12 mg Injection

Important Information

What is Lemtrada alemtuzumab?

Alemtuzumab is an antibody made from animal DNA.

Alemtuzumab is used to treat chronic B-cell lymphocytic leukemia or relapsing forms of multiple sclerosis.

Lemtrada is available only from a certified pharmacy under a special program.

Alemtuzumab may also be used for purposes not listed in this medication guide.

Alemtuzumab can cause life-threatening side effects.

Call your doctor if you have unusual bruising or bleeding, blood in your urine or vomit, swelling in your feet, fever, swollen glands, muscle aches, diarrhea, or if you feel very weak or tired.

Some side effects may occur during the injection or shortly afterward. You will be watched closely for at least 2 hours after receiving alemtuzumab.

Alemtuzumab can have long lasting effects on your body. You may need medical tests for up to 4 years after you stop using this medicine.

Before taking this medicine

You should not receive alemtuzumab if you are allergic to it. You should not be treated with Lemtrada if you have HIV (human immunodeficiency virus).

Tell your doctor if you have ever had:

an active or recent infection;
kidney disease;
a thyroid disorder;
a bleeding or blood clotting disorder such as hemophilia; or
if you have received a vaccine in the past 6 weeks.

Alemtuzumab may cause other types of cancer, such as melanoma, thyroid cancer, or blood cancers. Ask your doctor about this risk.

Alemtuzumab may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 4 months after your last dose. Tell your doctor if you become pregnant.

You should not breast-feed while using alemtuzumab.

How is alemtuzumab given?

Alemtuzumab is given as an infusion into a vein. How often you receive alemtuzumab will depend on why you are using this medicine. Follow your doctor’s instructions.

You may be given other medicines to help prevent certain side effects. Take these medicines for the full prescribed length of time.

You will be watched closely for at least 2 hours after receiving alemtuzumab, to make sure you do not have a serious reaction.

Alemtuzumab affects your immune system. You may get infections more easily, even serious or fatal infections. Your doctor will need to examine you on a regular basis.

Alemtuzumab can have long lasting effects on your body. You may need medical tests for up to 4 years after you stop using this medicine.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your alemtuzumab injection.

What happens if I overdose?

Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid while receiving alemtuzumab?

Avoid foods that may be a source of Listeria infection, or heat them thoroughly before consuming. This includes deli meat, undercooked meat, seafood, poultry, unpasteurized dairy products, or soft cheeses.

Avoid being near people who are sick or have infections. Avoid activities that may increase your risk of bleeding or injury.

Do not receive a “live” vaccine while using alemtuzumab, or you could develop a serious infection. Live vaccines include measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, varicella (chickenpox), and zoster (shingles).

Alemtuzumab side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some side effects may occur during the injection or shortly afterward. Tell your caregiver if you feel weak, dizzy, itchy, nauseated, chilled or feverish, or if you have chest tightness or trouble breathing.

Alemtuzumab can cause your immune system to attack cells and organs in your body. This can lead to life-threatening medical problems such as severe bleeding or kidney damage. Call your doctor right away if you have:

unusual bruising or bleeding;
blood in your urine;
swelling in your legs or feet; or
if you cough up blood.
Also call your doctor at once if you have:

pain or swelling in your neck or throat, trouble swallowing;
a mole that has changed in size or color;
gallbladder symptoms–stomach pain, fever, nausea, vomiting;
lung problems–cough, wheezing, chest pain, feeling short of breath;
signs of infection–fever, swollen glands, muscle aches, weakness, pale or yellowed skin, diarrhea, dark colored urine, pain or burning when you urinate;
symptoms of herpes virus–cold sores around your mouth, skin sores or blisters, itching, tingling, burning pain in your thigh or lower back; or
thyroid problems–extreme tired feeling, nervousness, fast heartbeats, heavy sweating, constipation, weight gain or loss, swelling of your eyes, feeling cold.
Common side effects may include:

nausea, vomiting, stomach pain, diarrhea;
headache, joint pain, back pain;
itching, rash, tingling;
dizziness, tiredness, sleep problems (insomnia);
vaginal itching or discharge;
stuffy nose, throat pain or itching, white patches in your mouth or throat; or
flushing (warmth, redness, or tingly feeling).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect alemtuzumab?

Tell your doctor about all your other medicines. Some may affect alemtuzumab, especially:

drugs that weaken the immune system such as cancer medicine, or medicines to prevent organ transplant rejection.
This list is not complete. Other drugs may affect alemtuzumab, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here. 

Follow the following prescription medicine precautions :

    Lemtrada may be harmful in pregnancy and there is a potential risk of miscarriage or carrying a child with birth defects if you or your partner becomes pregnant during this time. Take proper medical help in case you are pregnant, may be pregnant or planning to become pregnant in the near future.
  This medicine is not indicated for use in women. It is not known if  Lemtrada is excreted in human milk. Because of the potential for serious adverse reactions in nursing infants from Lemtrada, a decision should be made to either discontinue nursing, or discontinue the drug taking into account the importance of the drug to the mother.
  Your health care professional may recommend blood tests to see how your body is working. Blood tests help doctors check for certain diseases and conditions. They also help check the function of your organs and show how well treatments are working.
  Before taking Lemtrada, tell your doctor and pharmacist if you are allergic to Lemtrada, any other medications, or any of the ingredients in Lemtrada injection. This medicine is not recommended for use in patients with a known allergy to Lemtrada 12 mg.
  If you take Lemtrada, you must stop drinking alcohol. This is one of the ways to prevent this disease from getting worse. If you are dependent on alcohol and want to stop drinking, your doctor can recommend a therapy that’s tailored for your needs.
  If you use other prescription drugs or over the counter products at the same time, the effects of Lemtrada may change. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that your pharmacist can help you prevent or manage drug interactions.
  Missing a dose of Lemtrada can upset your treatment plan. If you do miss one of your doses, take it as soon as you remember, unless it’s almost time to take your next dose. In this case, you should just skip the missed dose. Don’t take a double dose to “make up” for the one you missed. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
  Do not take Lemtrada the use by (expiry) date printed on the pack. Do not take it if the packaging is torn or shows signs of tampering. If it has expired or is damaged, return it to your pharmacist for disposal.
  During your treatment with Lemtrada, it is very important for your doctor to know about your medical history if you have Kidney problems, liver problems, HIV, triglycerides, diabetes or other health problems.


What are the storage instructions for Lemtrada 12 mg ?

Patients must properly store the drug to retain its quality and efficacy. Following storage instructions will be helpful in storing the drug in the best of manner. 

  • Store Lemtrada at 20°C to 25°C (68°F to 77°F); excursions are permitted between 15°C and 30°C (59°F and 86°F).
  • Store it in a cool, dry place, protected from light and refrigerated when necessary. Improper storage can affect the effectiveness and shelf life of your medicine.
  • Consider storing your medications separately from your other family members. You can put them on a different shelf, or in a different cabinet or drawer.
  • If you’re driving, you may want to have certain medicines at hand, but don’t store them in the glove compartment, where they could be damaged from the heat, cold, or rain outside or from the car’s heater or air conditioner.
  •  Always remember to store your medication out of sight and reach of children and pets, to prevent accidental ingestion.

Prescription Required:

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The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.
Remember, keep this and all other medicines out of the reach of children and away from pets, never share your medicines with others, and use this medication only for the indication prescribed.

The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.


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