Abamune L : abacavir and lamivudine 300 Mg Tablets


Product Name : Abamune-L Tablets 30 Tablets/Pack
Also known as Kivexa and Epzicom
Active Ingredient : Abacavir 600mg and Lamivudine 300mg
Manufacturer : Cipla Pharmaceuticals
Product Type : Antiretroviral
SKU: ABACIPL30 Category: Tag:


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Abamune L tablets 600mg/300mg is a combination of abacavir and lamivudine which belong to a class of medicines called antiretroviral. This medicine is used to treat human immunodeficiency virus (HIV) infections in the adult it’s not a cure for HIV; it only prevents the virus from multiplying in the human body which can lead to AIDS (Acquired Immune Deficiency Syndrome) and other related illnesses, for example, AIDS-related Complexities or ARC.

How does Abamune-L work?

Abamune Tablet is an antiviral medication. The combination of abacavir and lamivudine helps to prevent the multiplication of further viruses in human cells. This stops the virus from producing new viruses and clears up your infection. HIV is responsible for acquired immune deficiency syndrome as HIV infection destroys CD4 (T) cells, which boost the body’s immune system. Since we know that a strong and healthy immune system helps fight infections and helps the human body to stay fit. Abamune-L does not cure AIDS or destroy HIV, but rather delay further damage to the immune system by stopping the production of new viruses.

Abamune-L does not reduce the risk of passing the infection to others. The patient needs to take precautions to prevent this from happening as HIV can still be passed on by sexual activity or by contamination with infected blood.

What does Abamune-L contain?

Abamune-L tablets contain abacavir 600mg and lamivudine 300mg as active ingredients, which are nucleoside reverse transcriptase inhibitors. Reverse transcriptase is a component of HIV required to infect cells so that more viruses can be produced, however, abacavir and lamivudine prevent transcriptase from functioning properly and actively. Abamune-L tablets also contain magnesium stearate, microcrystalline cellulose, and sodium starch glycollate as inactive ingredients.

Know the Side effects before you buy Abamune-L

Abamune-L tablets can cause some side effects. A few may be serious and other a few may disappear after a while; in case of serious side effects seek medical advice from a  health professional immediately as you may require medical attention. Abamune-L tablets contain both abacavir and lamivudine, the side effects reported for each of these have been combined. It has been reported that the most common side effects found in at least one to ten in every 100 people include nausea, vomiting, diarrhoea, upper abdominal pain, headache, high temperature, lethargy, fatigue, loss of appetite, hair loss, joint and muscle pain, abacavir hypersensitivity and skin rash. Less common side effects that could affect less than 1 in every 100 people may include increased liver enzyme production, anaemia (low red blood cell count), neutropenia (low white blood cell count), and reduced number of blood cells important for blood clotting.

The patient may show symptoms of tiredness or breathlessness if the production of red blood cells is reduced. A reduction in white blood cell count can make you more susceptible to infection.

Rare side effects which could affect less than one in every 1000 people are the breakdown of muscle tissue, increases of an enzyme called amylase and inflammation of the pancreas. Very rare side effects which could affect less than one in every 10,000 people are serious skin reactions and severe anaemia. It has been documented that any changes in fat distribution are associated with antiretroviral medications, which may include loss of fat from legs, arms and face and also increased fat in the abdomen and other internal organs, breasts and the back of the neck. Changes in the number of fatty substances and glucose in the blood have also been reported.

Within the first few weeks of commencing treatment with anti-HIV medicines, some people and in particular those that have been HIV positive for some time, may develop inflammatory reactions, for example, pain, redness, swelling and high temperature which may resemble an infection and may be severe. If you notice any changes in your health after commencing HIV treatment or become concerned with any new symptoms, then you should discuss this with your medical professional immediately.

If you experience any of the following, call your doctor immediately. Lactic Acidosis – if you become very sick with accelerated breathing, you may have a condition known as this. High acid levels in the blood can cause rapid breathing and can be life-threatening. This is more common in women than in men. If you experience allergic reactions soon after starting Abamune-L medication, for example wheezing, any swelling of the lips/mouth, difficulty in breathing, hay fever, hives or fainting then call your doctor immediately. Like all medications, there may be other side effects that occur in some people that are not listed or some side effects that are not yet known.

How should Abamune-L be taken?

Abamune-L tablets should be swallowed whole with a glass of water. You do not have to take this medication with food.

How much Abamune-L should I take?

Take Abamune-L tablets as directed by your medical professional. The normal dose for adults and adolescents is one tablet once a day, however, your medical professional may prescribe differently.

What to do if I take too much Abamune-L

You may need urgent medical attention if you have exceeded your recommended dosage. Even there is no sign of discomfort or poisoning, it is advisable to seek a doctor immediately.

Missed dose of Abamune-L

In case the recommended dosage is missed or forgotten, take it as soon as you remember and then continue as you normally would. Do not take more than one tablet to make up for the doses you have missed.

How long should Abamune-L be taken for?

Abamune-L is only to control the adverse medical condition; it does not entirely cure it, however, the patient needs to take the recommended dosage every day. Do not stop taking the prescribed Abamune-L tablets or alter the dose without medical consultation.


Abamune L is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body. It is generally used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). This medicine is for adults and children who are at least 3 months old.

This is to highlight that this medicine is not a cure for HIV or AIDS.


Sleep problems, strange dreams; headache, tiredness; nausea or vomiting;

changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist); or (in children) stuffy nose, sneezing, sore throat, ear pain.

It can cause other serious side effects that may not be signs of an allergic reaction. Call your doctor at once if you have:

  • the first sign of any skin rash, no matter how mild; chest pain or pressure, pain spreading to your jaw or shoulder;
  • severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate; or
  • Liver problems–nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-coloured stools, jaundice (yellowing of the skin or eyes).
  • signs of a new infection–fever, night sweats, swollen glands, mouth sores, diarrhoea, stomach pain, weight loss;
  • chest pain (especially when you breathe), dry cough, wheezing, feeling short of breath;


 You need to remember certain points such as –


abamune L harmful during pregnancy

Abamune L medicine may be harmful in pregnancy and there is a potential risk of miscarriage or carrying a child with birth defects if you or your partner become pregnant during this time. Also tell your pharmacist if you plan to become pregnant at any time in the future, because Abacavir Sulfate 300 Mg may remain in your body for years after you stop taking it.
 women infected with HIV should not breastfeed It is also recommended that women infected with HIV should not breastfeed their infants, regardless of their treatment, to avoid transmitting the virus to the baby in breast milk. To get more information, you need to discuss this with your doctor.
 have regular blood tests You will need to have regular blood tests and check-ups during your treatment with Abacavir. Blood tests help doctors check for certain diseases and conditions. They also help check the function of your organs and show how well the treatment is working
 Tell your doctor Tell your doctor if you have ever had any unusual or allergic reaction to this or any other medicines. Also inform your health care professional, in case you have any other type of allergies, such as to foods, dyes, preservatives, or animals. This HIV medicine is not recommended for use to patients who have an allergy to Abamune L.
  In general, drinking alcoholic beverages should be kept to a minimum or avoided completely. If you are dependent on alcohol and want to stop drinking, your doctor can recommend a therapy that’s tailored for your needs.
 inform your doctor Before using or buying Abamune L, inform your doctor or pharmacist if you are taking or have recently taken any prescribed or non-prescribed drugs (e.g. vitamins, herbal supplements, etc.) so that your pharmacist can help you prevent or manage drug interactions.
 follow schedule for Abamune L If you miss a dose of Abamune L, take the missed dose as soon as you remember it. If it is close to the time of your next dose, skip the missed dose and resume your dosing schedule as per prescription. Do not use extra doses to make up for a missed dose. Do consult your doctor to discuss changes in your dosing schedule or a new schedule to make up for missed doses, if you have missed too many doses recently.
 check tablet expiry date Taking a single dose of expired medicine is unlikely to produce an adverse event. Expired drugs may become ineffective in treating your prescribed conditions. To be on the safer side, it is advisable not to use an expired drug. If you’ve had medicine for a while, check the expiry date before using it. If it has expired or is damaged, return it to your pharmacist for disposal. Checking the expiry date is as important as taking the right medicine.
  Before using or buying Abamune L, tell your doctor or pharmacist your medical history, especially if you have liver problems (including hepatitis B or C infection), diabetes, haemophilia (a bleeding disorder), heart or pancreas problems, or low blood potassium levels, etc to avoid side effects or any other problem.


What are the storage instructions for  Abamune L?

Once buy abamune L, you must be properly stored to retain its quality and efficacy. Following storage instructions will help to store the drug in the best condition.

  • Store  Abamune L  at 20°C to 25°C (68°F to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F).
  • Consider storing your medications separately from other medicines used by other members. It will lessen the possibility of taking the wrong medicine.
  • Make sure to keep medicine out of the reach of children and pets.
  • Store in the original container. Do not use it if the original seal over the container opening is broken or missing.
  • Store Abamune L in a dry place (Not in the bathroom). Improper storage can affect the effectiveness and shelf life of your medicine.

A patient must keep a written list ready for all of the prescription and non-prescription (over-the-counter) medicines, as well as any products such as vitamins, minerals, or other dietary supplements. If you are admitted to a hospital,  you should bring this list with you each time. During emergencies, this list is also very important.

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The information provided here is for general educational purposes only. Does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.

Remember, keep Abamune L and all other medicines out of the reach of children and away from pets. Never share your medicines with others, and use this medication only for the indication prescribed.

The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. In case you have any query related to the drugs you are taking, check with your doctor, nurse or pharmacist & feel free reach out our support team before you buy abamune L.


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