Description
Why is this medication prescribed?
Decitabine is used to treat myelodysplastic syndrome (a group of conditions in which the bone marrow produces blood cells that are misshapen and does not produce enough healthy blood cells). Decitabine is in a class of medications called hypomethylation agents. It works by helping the bone marrow produce normal blood cells and by killing abnormal cells in the bone marrow.
How should this medicine be used?
Decitabine comes as a powder to be to be added to fluid and injected slowly over 3 hours intravenously (into a vein) by a doctor or nurse in a medical office or hospital outpatient clinic. It is usually injected every 8 hours for 3 days. This treatment period is called a cycle, and the cycle may be repeated every 6 weeks for as long as your doctor recommends. Decitabine should usually be given for at least four cycles but may be continued if your doctor decides that you will benefit from additional treatment.
Your doctor may also need to delay your treatment and reduce your dose if you experience certain side effects. Be sure to tell your doctor how you are feeling during your treatment with decitabine.
Your doctor will give you medication to prevent nausea and vomiting before you receive each dose of decitabine.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before receiving a dose of decitabine,
- tell your doctor and pharmacist if you are allergic to decitabine or any other medications.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor if you have kidney or liver disease.
- tell your doctor if you are pregnant or plan to become pregnant, or if you plan to father a child. You or your partner should not become pregnant while you are using decitabine. You should use birth control to prevent pregnancy in yourself or your partner during your treatment with decitabine and for 2 months afterwards. Talk to your doctor about birth control methods that will work for you. If you or your partner becomes pregnant while using decitabine, call your doctor. Decitabine may harm the fetus.
- tell your doctor if you are breast-feeding.
What special dietary instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
What should I do if I forget a dose?
Call your doctor right away if you are unable to keep an appointment to receive a dose of decitabine.
What side effects can this medication cause?
Decitabine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- excessive tiredness
- pale skin
- headache
- dizziness
- confusion
- fast heartbeat
- difficulty falling asleep or staying asleep
- weakness
- shortness of breath
- nausea
- constipation
- diarrhea
- vomiting
- stomach pain
- heartburn or indigestion
- painful sores in mouth, or on tongue or lips
- red spots on the skin
- rash
- change in skin color
- hair loss
- joint or muscle pain
- chest discomfort or chest wall pain
- swelling of the hands, feet, ankles, lower legs, or stomach
- pain, swelling, or redness at injection spot
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
- unusual bleeding or bruising
- hives
- itching
- difficulty breathing or swallowing
- swelling of the face
- sore throat, fever, chills, cough, or other signs of infection
Call your doctor immediately if you have any of the following symptoms of hyperglycemia (high blood sugar):
- extreme thirst
- frequent urination
- extreme hunger
- weakness
- blurred vision
Decitabine may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
In case of emergency/overdose
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can’t be awakened, immediately call emergency services at 911.
Symptoms of overdose may include:
- unusual bleeding or bruising
- sore throat, fever, chills, cough, or other signs of infection
What other information should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body’s response to decitabine.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Follow the following prescription medicine precautions :
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Decitabine may be harmful for your baby during pregnancy. Take proper medical help in case you are pregnant, may be pregnant or planning to become pregnant in the near future. |
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This medicine is not indicated for use in women. It is not known if Natdecita is excreted in human milk. Because of the potential for serious adverse reactions in nursing infants from Decitabine a decision should be made to either discontinue nursing, or discontinue the drug taking into account the importance of the drug to the mother. |
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Your health care professional can check blood tests to regularly monitor your liver and kidney function, while you are taking Decitabine . It is also important to check your levels of blood cells and other substances in the blood. |
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Before taking this medicine, tell your doctor and pharmacist if you are allergic to Decitabine , any other medications, or any of the ingredients in Decitabine medicine. This medication is not recommended for use in patients with a known allergy to Decitabine . |
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If you take Alimta, you must stop drinking alcohol. This is one of the ways to prevent this disease from getting worse. If you are dependent on alcohol and want to stop drinking, your doctor can recommend a therapy that’s tailored for your needs. |
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If you use other prescription drugs or over the counter products at the same time, the effects of this cancer medicine may change. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that your pharmacist can help you prevent or manage drug interactions. |
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Missing a dose of Decitabine can upset your treatment plan. If you do miss one of your doses, take it as soon as you remember, unless it’s almost time to take your next dose. In this case, you should just skip the missed dose. Don’t take a double dose to “make up” for the one you missed. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice. |
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Do not take Natdecita the use by (expiry) date printed on the pack. Do not take it if the packaging is torn or shows signs of tampering. If it has expired or is damaged, return it to your pharmacist for disposal. |
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During your treatment with Decitabine, it is very important for your doctor to know about your medical history if you have Kidney problems, hepatitis, liver problems, HIV (human immunodeficiency virus), triglycerides, diabetes or other health problems. |
What are the storage instructions for Decitabine ?
Patients must properly store the drug to retain its quality and efficacy. Following storage instructions will be helpful in storing the drug in the best of manner.
- Store intact vials at room temperature of 25°C (77°F); excursions permitted to 15°C to 30°C (59°F to 86°F). Reconstituted solution and infusion solution are stable for 24 hours when refrigerated at 2°C to 8°C (36°F to 46°F).
- When you aren’t injecting, store Decitabine Pre-filled syringes in a place that’s protected from light.
- Make sure to always keep your medicine in an area of your home that is out of the reach of children and pets.
- Do not use Natdecita if the liquid in the vial looks discolored or cloudy, or if the liquid has lumps, flakes, or particles.
- Do not freeze CDecitabine.
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Prescription Required:
In order to legally purchase this medicine from Anticancercure.com, you’ll require a prescription from your Registered Medical Practitioner.
Note:
The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.
Remember, keep this and all other medicines out of the reach of children and away from pets, never share your medicines with others, and use this medication only for the indication prescribed.
The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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